Orthospect Neuro

fMRI during passive movement
Figure legend: The image shows BOLD fMRI slices of a human brain during passive movement of the right leg of a healthy subject. Regions with enhanced neuronal activity were identified in the motor cortex as well as in the sensory cortex and are shown as pseudo-color overlay. Images were acquired with a 3T whole-body MR scanner (Siemens Magnetom Skyra, Erlangen, Germany) by using an fMRI sequence with online motion correction.
Open picture gallery (1 image)
Figure legend: The image shows BOLD fMRI slices of a human brain during passive movement of the right leg of a healthy subject. Regions with enhanced neuronal activity were identified in the motor cortex as well as in the sensory cortex and are shown as pseudo-color overlay. Images were acquired with a 3T whole-body MR scanner (Siemens Magnetom Skyra, Erlangen, Germany) by using an fMRI sequence with online motion correction.
Enhancing the field of fMRI

Functional MRI (fMRI) studies of the brain are based on the observation that neuronal activity is coupled to cerebral blood flow. One form of fMRI, so called blood-oxygen-level-dependent (BOLD) MRI, permits the visualization of areas with enhanced neuronal activity by detecting the increased inflow of oxygenated blood to the respective regions of the brain. Therefore, fMRI is the most important non-invasive tool to study the functions of different neuronal networks. In addition, fMRI can help by testing the integrity of spinal cord and its neuronal response after spinal injury. At the moment, the integrity of neuronal pathways in the spinal cord is evaluated by electroencephalography (EEG), a technique where the electrical activity of the brain is recorded via electrodes placed on the scalp. The major drawback of EEG is its limited spatial resolution of a few centimetres. Therefore, alternative pathways for signal transmission might be identified which can provide information about regenerative processes. In close collaboration with the Medical University of Innsbruck, Austria, the Ergospect GmbH developes a new device, the Orthospect Neuro module, which enables a passive movement of the lower extremities of patients affected by spinal trauma. Thus, it is possible to study the integrity of neuronal pathways after spinal trauma by measuring neuronal activity in the brain by fMRI during passive movement of the lower extremities. At the moment, first experiments are carried out in healthy probands to optimize the measuring protocols and product design.

NEWS

Good News!

We are excited to announce our newsletter providing interesting and important information of our in-bore MRI devices to our readers and users!

Project Genuspect

Ergospect starts the development of a MR conditional knee ergometer for reliable diagnosis and fast treatment

Orthospect Neuro – Enhancing the field of fMRI

fMRI studies of the brain are based on the observation that neuronal activity is coupled to cerebral blood flow.
Read moreRead more

NEWS ARCHIVE

Ergospect medical technology